ALTERIO, VINCENZO
ALTERIO, VINCENZO
Istituto di Biostrutture e Bioimmagini - IBB - Sede Napoli
2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site
2020 Bozdag, Murat; Supuran, Claudiu T.; Esposito, Davide; Angeli, Andrea; Carta, Fabrizio; Monti, Simona Maria; De Simone, Giuseppina; Alterio, Vincenzo
A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors
2023 Langella, Emma; Esposito, Davide; Monti, Simona Maria; Supuran, Claudiu T.; De Simone, Giuseppina; Alterio, Vincenzo
A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity
2020 Sarnella, Annachiara; D'Avino, Giuliana; Hill Billy, Samuel; Alterio, Vincenzo; Winum, Jeanyves; Supuran Claudiu, T; DE SIMONE, Giuseppina; Zannetti, Antonella
Benzoxaborole as a new chemotype for carbonic anhydrase inhibition
2016 Alterio, Vincenzo; Cadoni, Roberta; Esposito, Davide; Vullo, Daniela; DI FIORE, Anna; Monti, SIMONA MARIA; Caporale, Andrea; Ruvo, Menotti; Sechi, Mario; Dumy, Pascal; Supuran Claudiu, T; DE SIMONE, Giuseppina; Winum, Jeanyves
Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule
2021 DE SIMONE, Giuseppina; Alterio, Vincenzo
Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex
2019 Alterio, Vincenzo; Kellner, Markus; Esposito, Davide; Lieschestarnecker, Friederike; Bua, Silvia; Supuran Claudiu, T; Monti, SIMONA MARIA; Zeidler, Reinhard; DE SIMONE, Giuseppina
Biochemical characterization of the chloroplastic beta-carbonic anhydrase from Flaveria bidentis (L.) "Kuntze"
2014 Dathan NA; Alterio V; Troiano E; Vullo D; Ludwig M; De Simone G; Supuran CT; Monti SM.
Cadmium-containing carbonic anhydrase CDCA1 in marine diatom Thalassiosira weissflogii
2015 Alterio, Vincenzo; Langella, Emma; DE SIMONE, Giuseppina; Monti, SIMONA MARIA
Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors
2009 Vitale RM; Alterio V; Innocenti A; Winum JY; Monti SM; De Simone G; Supuran CT.
Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides - Solution and crystallographic studies
2007 Alterio V; De Simone G; Monti SM; Scozzafava A; Supuran CT.
Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II.
2005 Menchise, V; De Simone, G; Alterio, V; Di Fiore, A; Pedone, C; Scozzafava, A; Supuran, Ct
Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX
2006 Alterio, Vincenzo; Vitale, ROSA MARIA; Monti, SIMONA MARIA; Pedone, Carlo; Scozzafava, Andrea; Cecchi, Alessandro; DE SIMONE, Giuseppina; Supuran Claudiu, T
Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors
2012 Truppo, E; Supuran, Ct; Sandomenico, A; Vullo, D; Innocenti, A; Di Fiore, A; Alterio, V; De Simone, G; Monti, Sm
Carbonic anhydraseinhibitors: X-ray crystallographic studies for the binding of N-substitutedbenzenesulfonamides to human isoform II
2011 Di Fiore, A; Maresca, A; Alterio, V; Supuran, Ct; De Simone, G
Crystal structure of an S-formylglutathione hydrolase from pseudoalteromonas haloplanktis TAC125.
2010 Alterio, V; Aurilia, V; Romanelli, A; Parracino, A; Saviano, M; D'Auria, S; De Simone, G
Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide.
2010 Dathan, NINA ALAYNE; DE SIMONE, Giuseppina; Monti, SIMONA MARIA; Alterio, Vincenzo; DI FIORE, Anna
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX.
2009 Alterio, V; Hilvo, M; Di Fiore, A; Supuran, Ct; Pan, P; Parkkila, S; Scaloni, A; Pastorek, J; Pastorekova, S; Pedone, C; Scozzafava, A; Monti, Sm; De Simone, G
Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor
2018 Alterio V.; Esposito D.; Monti S.M.; Supuran C.T.; De Simone G.
Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense
2015 De Simone, G; Monti, Sm; Alterio, V; Buonanno, M; De Luca, V; Rossi, M; Carginale, V; Supuran, Ct; Capasso, C; Di Fiore, A
Disclosing the interaction of carbonic anhydrase ix with cullin-associated nedd8-dissociated protein 1 by molecular modeling and integrated binding measurements.
2017 Buonanno, M; Langella, E; Zambrano, N; Succoio, M; Sasso, E; Alterio, V; Di Fiore, A; Sandomenico, A; Supuran, Ct; Scaloni, A; Monti, Sm; De Simone, G
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site | 1-gen-2020 | Bozdag, Murat; Supuran, Claudiu T.; Esposito, Davide; Angeli, Andrea; Carta, Fabrizio; Monti, Simona Maria; De Simone, Giuseppina; Alterio, Vincenzo | |
| A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors | 1-gen-2023 | Langella, Emma; Esposito, Davide; Monti, Simona Maria; Supuran, Claudiu T.; De Simone, Giuseppina; Alterio, Vincenzo | |
| A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity | 1-gen-2020 | Sarnella, Annachiara; D'Avino, Giuliana; Hill Billy, Samuel; Alterio, Vincenzo; Winum, Jeanyves; Supuran Claudiu, T; DE SIMONE, Giuseppina; Zannetti, Antonella | |
| Benzoxaborole as a new chemotype for carbonic anhydrase inhibition | 1-gen-2016 | Alterio, Vincenzo; Cadoni, Roberta; Esposito, Davide; Vullo, Daniela; DI FIORE, Anna; Monti, SIMONA MARIA; Caporale, Andrea; Ruvo, Menotti; Sechi, Mario; Dumy, Pascal; Supuran Claudiu, T; DE SIMONE, Giuseppina; Winum, Jeanyves | |
| Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule | 1-gen-2021 | DE SIMONE, Giuseppina; Alterio, Vincenzo | |
| Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex | 1-gen-2019 | Alterio, Vincenzo; Kellner, Markus; Esposito, Davide; Lieschestarnecker, Friederike; Bua, Silvia; Supuran Claudiu, T; Monti, SIMONA MARIA; Zeidler, Reinhard; DE SIMONE, Giuseppina | |
| Biochemical characterization of the chloroplastic beta-carbonic anhydrase from Flaveria bidentis (L.) "Kuntze" | 1-gen-2014 | Dathan NA; Alterio V; Troiano E; Vullo D; Ludwig M; De Simone G; Supuran CT; Monti SM. | |
| Cadmium-containing carbonic anhydrase CDCA1 in marine diatom Thalassiosira weissflogii | 1-gen-2015 | Alterio, Vincenzo; Langella, Emma; DE SIMONE, Giuseppina; Monti, SIMONA MARIA | |
| Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors | 1-gen-2009 | Vitale RM; Alterio V; Innocenti A; Winum JY; Monti SM; De Simone G; Supuran CT. | |
| Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides - Solution and crystallographic studies | 1-gen-2007 | Alterio V; De Simone G; Monti SM; Scozzafava A; Supuran CT. | |
| Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II. | 1-gen-2005 | Menchise, V; De Simone, G; Alterio, V; Di Fiore, A; Pedone, C; Scozzafava, A; Supuran, Ct | |
| Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX | 1-gen-2006 | Alterio, Vincenzo; Vitale, ROSA MARIA; Monti, SIMONA MARIA; Pedone, Carlo; Scozzafava, Andrea; Cecchi, Alessandro; DE SIMONE, Giuseppina; Supuran Claudiu, T | |
| Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors | 1-gen-2012 | Truppo, E; Supuran, Ct; Sandomenico, A; Vullo, D; Innocenti, A; Di Fiore, A; Alterio, V; De Simone, G; Monti, Sm | |
| Carbonic anhydraseinhibitors: X-ray crystallographic studies for the binding of N-substitutedbenzenesulfonamides to human isoform II | 1-gen-2011 | Di Fiore, A; Maresca, A; Alterio, V; Supuran, Ct; De Simone, G | |
| Crystal structure of an S-formylglutathione hydrolase from pseudoalteromonas haloplanktis TAC125. | 1-gen-2010 | Alterio, V; Aurilia, V; Romanelli, A; Parracino, A; Saviano, M; D'Auria, S; De Simone, G | |
| Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide. | 1-gen-2010 | Dathan, NINA ALAYNE; DE SIMONE, Giuseppina; Monti, SIMONA MARIA; Alterio, Vincenzo; DI FIORE, Anna | |
| Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX. | 1-gen-2009 | Alterio, V; Hilvo, M; Di Fiore, A; Supuran, Ct; Pan, P; Parkkila, S; Scaloni, A; Pastorek, J; Pastorekova, S; Pedone, C; Scozzafava, A; Monti, Sm; De Simone, G | |
| Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor | 1-gen-2018 | Alterio V.; Esposito D.; Monti S.M.; Supuran C.T.; De Simone G. | |
| Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense | 1-gen-2015 | De Simone, G; Monti, Sm; Alterio, V; Buonanno, M; De Luca, V; Rossi, M; Carginale, V; Supuran, Ct; Capasso, C; Di Fiore, A | |
| Disclosing the interaction of carbonic anhydrase ix with cullin-associated nedd8-dissociated protein 1 by molecular modeling and integrated binding measurements. | 1-gen-2017 | Buonanno, M; Langella, E; Zambrano, N; Succoio, M; Sasso, E; Alterio, V; Di Fiore, A; Sandomenico, A; Supuran, Ct; Scaloni, A; Monti, Sm; De Simone, G |