ALTERIO, VINCENZO
ALTERIO, VINCENZO
Istituto di Biostrutture e Bioimmagini - IBB - Sede Napoli
Exploring the binding mode of phenyl and vinyl boronic acids to human carbonic anhydrases
2024 Esposito, Davide; Monti, Simona Maria; Supuran, Claudiu T.; Winum, Jean-Yves; De Simone, Giuseppina; Alterio, Vincenzo
6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: In Silico Design, Synthesis, and X-ray Crystallography
2023 Nocentini, Alessio; Bonardi, Alessandro; Bazzicalupi, Carla; Alterio, Vincenzo; Esposito, Davide; Monti, SIMONA MARIA; Smietana, Michael; DE SIMONE, Giuseppina; Supuran, Claudiu T.; Gratteri, Paola; Winum, Jean-Yves
A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors
2023 Langella, Emma; Esposito, Davide; Monti, SIMONA MARIA; Supuran, Claudiu T.; DE SIMONE, Giuseppina; Alterio, Vincenzo
Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for μ Opioid receptor for Safer and long-lasting analgesia
2023 Angeli, Andrea; Micheli, Laura; Turnaturi, Rita; Pasquinucci, Lorella; Parenti, Carmela; Alterio, Vincenzo; DI FIORE, Anna; DE SIMONE, Giuseppina; Monti, SIMONA MARIA; Carta, Fabrizio; Mannelli Lorenzo Di, Cesare; Ghelardini, Carla; Supuran Claudiu, T
Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion
2022 Sarnella, Annachiara; Ferrara, Ylenia; Auletta, Luigi; Albanese, Sandra; Cerchia, Laura; Alterio, Vincenzo; DE SIMONE, Giuseppina; Supuran, C. T.; Zannetti, Antonella
α-CAs from Photosynthetic Organisms
2022 Langella, Emma; Di Fiore, Anna; Alterio, Vincenzo; Monti, Simona Maria; De Simone, Giuseppina; D’Ambrosio, Katia
Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule
2021 De Simone, G; Bua, S; Supuran, Ct; Alterio, V
Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms?
2021 Alterio, Vincenzo; Langella, Emma; Buonanno, Martina; Esposito, Davide; Nocentini, A.; Berrino, E.; Bua, S.; Polentarutti, M.; Supuran, C. T.; Monti, SIMONA MARIA; DE SIMONE, Giuseppina
2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site
2020 Bozdag, Murat; Supuran Claudiu, T; Esposito, Davide; Angeli, Andrea; Carta, Fabrizio; Monti, SIMONA MARIA; DE SIMONE, Giuseppina; Alterio, Vincenzo
A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity
2020 Sarnella, Annachiara; D'Avino, Giuliana; Hill, Billy Samuel; Alterio, Vincenzo; Winum, Jeanyves; Supuran Claudiu, T; DE SIMONE, Giuseppina; Zannetti, Antonella
Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy
2020 Nocentini, Alessio; Alterio, Vincenzo; Bua, Silvia; Micheli, Laura; Esposito, Davide; Buonanno, Martina; Bartolucci, Gianluca; Osman Sameh, M; ALOthman Zeid, A; Cirilli, Roberto; Pierini, Marco; Monti, SIMONA MARIA; Mannelli Lorenzo Di, Cesare; Gratteri, Paola; Ghelardini, Carla; DE SIMONE, Giuseppina; Supuran Claudiu, T
Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex
2019 Alterio, Vincenzo; Kellner, Markus; Esposito, Davide; Lieschestarnecker, Friederike; Bua, Silvia; Supuran Claudiu, T; Monti, SIMONA MARIA; Zeidler, Reinhard; DE SIMONE, Giuseppina
Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity
2019 Langella, Emma; Alterio, Vincenzo; D'Ambrosio, Katia; Cadoni, Roberta; Winum, Jeanyves; Supuran Claudiu, T; Monti, SIMONA MARIA; DE SIMONE, Giuseppina; DI FIORE, Anna
Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor
2018 Alterio, V; Esposito, D; Monti, Sm; Supuran, Ct; De Simone, G
Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one
2018 Supuran Claudiu, T; Alterio, Vincenzo; DI FIORE, Anna; D'Ambrosio, Katia; Carta, Fabrizio; Monti, SIMONA MARIA; DE SIMONE, Giuseppina
Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding
2018 DE SIMONE, Giuseppina; Angeli, Andrea; Bozdag, Murat; Supuran Claudiu, T; Winum, Jeanyves; Monti, SIMONA MARIA; Alterio, Vincenzo
Disclosing the interaction of carbonic anhydrase ix with cullin-associated nedd8-dissociated protein 1 by molecular modeling and integrated binding measurements.
2017 Buonanno, M; Langella, E; Zambrano, N; Succoio, M; Sasso, E; Alterio, V; Di Fiore, A; Sandomenico, A; Supuran, Ct; Scaloni, A; Monti, Sm; De Simone, G
Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations
2017 DE SIMONE, Giuseppina; Langella, Emma; Esposito, Davide; Supuran Claudiu, T; Monti, SIMONA MARIA; Winum Jean, Yves; Alterio, Vincenzo
Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides
2017 Bruno, Elvira; Buemi Maria, Rosa; DI FIORE, Anna; De Luca, Laura; Ferro, Stefania; Angeli, Andrea; Cirilli, Roberto; Sadutto, Daniele; Alterio, Vincenzo; Monti, SIMONA MARIA; Supuran Claudiu, T; DE SIMONE, Giuseppina; Gitto, Rosaria
Benzoxaborole as a new chemotype for carbonic anhydrase inhibition
2016 Alterio, Vincenzo; Cadoni, Roberta; Esposito, Davide; Vullo, Daniela; DI FIORE, Anna; Monti, SIMONA MARIA; Caporale, Andrea; Ruvo, Menotti; Sechi, Mario; Dumy, Pascal; Supuran Claudiu, T; DE SIMONE, Giuseppina; Winum, Jeanyves
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Exploring the binding mode of phenyl and vinyl boronic acids to human carbonic anhydrases | 1-gen-2024 | Esposito, Davide; Monti, Simona Maria; Supuran, Claudiu T.; Winum, Jean-Yves; De Simone, Giuseppina; Alterio, Vincenzo | |
| 6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: In Silico Design, Synthesis, and X-ray Crystallography | 1-gen-2023 | Nocentini, Alessio; Bonardi, Alessandro; Bazzicalupi, Carla; Alterio, Vincenzo; Esposito, Davide; Monti, SIMONA MARIA; Smietana, Michael; DE SIMONE, Giuseppina; Supuran, Claudiu T.; Gratteri, Paola; Winum, Jean-Yves | |
| A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors | 1-gen-2023 | Langella, Emma; Esposito, Davide; Monti, SIMONA MARIA; Supuran, Claudiu T.; DE SIMONE, Giuseppina; Alterio, Vincenzo | |
| Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for μ Opioid receptor for Safer and long-lasting analgesia | 1-gen-2023 | Angeli, Andrea; Micheli, Laura; Turnaturi, Rita; Pasquinucci, Lorella; Parenti, Carmela; Alterio, Vincenzo; DI FIORE, Anna; DE SIMONE, Giuseppina; Monti, SIMONA MARIA; Carta, Fabrizio; Mannelli Lorenzo Di, Cesare; Ghelardini, Carla; Supuran Claudiu, T | |
| Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion | 1-gen-2022 | Sarnella, Annachiara; Ferrara, Ylenia; Auletta, Luigi; Albanese, Sandra; Cerchia, Laura; Alterio, Vincenzo; DE SIMONE, Giuseppina; Supuran, C. T.; Zannetti, Antonella | |
| α-CAs from Photosynthetic Organisms | 1-gen-2022 | Langella, Emma; Di Fiore, Anna; Alterio, Vincenzo; Monti, Simona Maria; De Simone, Giuseppina; D’Ambrosio, Katia | |
| Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule | 1-gen-2021 | De Simone, G; Bua, S; Supuran, Ct; Alterio, V | |
| Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms? | 1-gen-2021 | Alterio, Vincenzo; Langella, Emma; Buonanno, Martina; Esposito, Davide; Nocentini, A.; Berrino, E.; Bua, S.; Polentarutti, M.; Supuran, C. T.; Monti, SIMONA MARIA; DE SIMONE, Giuseppina | |
| 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site | 1-gen-2020 | Bozdag, Murat; Supuran Claudiu, T; Esposito, Davide; Angeli, Andrea; Carta, Fabrizio; Monti, SIMONA MARIA; DE SIMONE, Giuseppina; Alterio, Vincenzo | |
| A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity | 1-gen-2020 | Sarnella, Annachiara; D'Avino, Giuliana; Hill, Billy Samuel; Alterio, Vincenzo; Winum, Jeanyves; Supuran Claudiu, T; DE SIMONE, Giuseppina; Zannetti, Antonella | |
| Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy | 1-gen-2020 | Nocentini, Alessio; Alterio, Vincenzo; Bua, Silvia; Micheli, Laura; Esposito, Davide; Buonanno, Martina; Bartolucci, Gianluca; Osman Sameh, M; ALOthman Zeid, A; Cirilli, Roberto; Pierini, Marco; Monti, SIMONA MARIA; Mannelli Lorenzo Di, Cesare; Gratteri, Paola; Ghelardini, Carla; DE SIMONE, Giuseppina; Supuran Claudiu, T | |
| Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex | 1-gen-2019 | Alterio, Vincenzo; Kellner, Markus; Esposito, Davide; Lieschestarnecker, Friederike; Bua, Silvia; Supuran Claudiu, T; Monti, SIMONA MARIA; Zeidler, Reinhard; DE SIMONE, Giuseppina | |
| Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity | 1-gen-2019 | Langella, Emma; Alterio, Vincenzo; D'Ambrosio, Katia; Cadoni, Roberta; Winum, Jeanyves; Supuran Claudiu, T; Monti, SIMONA MARIA; DE SIMONE, Giuseppina; DI FIORE, Anna | |
| Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor | 1-gen-2018 | Alterio, V; Esposito, D; Monti, Sm; Supuran, Ct; De Simone, G | |
| Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one | 1-gen-2018 | Supuran Claudiu, T; Alterio, Vincenzo; DI FIORE, Anna; D'Ambrosio, Katia; Carta, Fabrizio; Monti, SIMONA MARIA; DE SIMONE, Giuseppina | |
| Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding | 1-gen-2018 | DE SIMONE, Giuseppina; Angeli, Andrea; Bozdag, Murat; Supuran Claudiu, T; Winum, Jeanyves; Monti, SIMONA MARIA; Alterio, Vincenzo | |
| Disclosing the interaction of carbonic anhydrase ix with cullin-associated nedd8-dissociated protein 1 by molecular modeling and integrated binding measurements. | 1-gen-2017 | Buonanno, M; Langella, E; Zambrano, N; Succoio, M; Sasso, E; Alterio, V; Di Fiore, A; Sandomenico, A; Supuran, Ct; Scaloni, A; Monti, Sm; De Simone, G | |
| Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations | 1-gen-2017 | DE SIMONE, Giuseppina; Langella, Emma; Esposito, Davide; Supuran Claudiu, T; Monti, SIMONA MARIA; Winum Jean, Yves; Alterio, Vincenzo | |
| Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides | 1-gen-2017 | Bruno, Elvira; Buemi Maria, Rosa; DI FIORE, Anna; De Luca, Laura; Ferro, Stefania; Angeli, Andrea; Cirilli, Roberto; Sadutto, Daniele; Alterio, Vincenzo; Monti, SIMONA MARIA; Supuran Claudiu, T; DE SIMONE, Giuseppina; Gitto, Rosaria | |
| Benzoxaborole as a new chemotype for carbonic anhydrase inhibition | 1-gen-2016 | Alterio, Vincenzo; Cadoni, Roberta; Esposito, Davide; Vullo, Daniela; DI FIORE, Anna; Monti, SIMONA MARIA; Caporale, Andrea; Ruvo, Menotti; Sechi, Mario; Dumy, Pascal; Supuran Claudiu, T; DE SIMONE, Giuseppina; Winum, Jeanyves |