MILANI DE MAYO DE MARI, MARIO
MILANI DE MAYO DE MARI, MARIO
Istituto di Biofisica - IBF - Sede Secondaria Milano
Structural snapshots of the aldol condensation reaction of the enzyme trans-o-hydroxybenzylidenepyruvate hydratase-aldolase from Pseudomonas fluorescens N3
2025 Ferrara, Silvia; Braggiotti, Bianca; Mastrangelo, Eloise; Di Gennaro, Patrizia; Bertoni, Giovanni; Milani, Mario
4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses
2024 Puxeddu, M.; Donalisio, M.; Bugert, J. J.; Corona, A.; Cocomazzi, P.; MILANI DE MAYO DE MARI, Mario; Hucke, F.; Arduino, I.; Esposito, F.; Moretti, P.; Ortore, M. G.; Nalli, M.; Manetto, S.; Mazzoccanti, G.; Bigogno, C.; Dondio, G.; Scio, P.; Coluccia, A.; Fracella, M.; Antonelli, G.; Lembo, D.; Tramontano, E.; Silvestri, R.; Mastrangelo, E.; La Regina, G.
Acid-sensing ion channel 3 is a new potential therapeutic target for the control of glioblastoma cancer stem cells growth
2024 Balboni, Andrea; D'Angelo, Camilla; Collura, Nicoletta; Brusco, Simone; Di Berardino, Claudia; Targa, Altea; Massoti, Beatrice; Mastrangelo, Eloise; Milani, Mario; Seneci, Pierfausto; Broccoli, Vania; Muzio, Luca; Galli, Rossella; Menegon, Andrea
CHCHD4 binding affects the active site of apoptosis inducing factor (AIF): Structural determinants for allosteric regulation
2024 Fagnani, E.; Cocomazzi, P.; Pellegrino, S.; Tedeschi, G.; Scalvini, F. G.; Cossu, F.; Da Vela, S.; Aliverti, A.; Mastrangelo, E.; Milani, M.
Notte Europea delle Ricercatrici e dei Ricercatori 2024: Grande come un virus
2024 Massa, Claudia; Mastrangelo, Eloise; Bollati, Michela; Cossu, Federica; Zoppè, Monica; Milani De Mayo De Mari, Mario; De Rosa, Matteo; Ferrara, Silvia; Boni', Francesco.
Stabilization of the retromer complex: Analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface
2024 Fagnani, E.; Bonì, F.; Seneci, P.; Gornati, D.; Muzio, L.; Mastrangelo, E.; MILANI DE MAYO DE MARI, Mario
The antipsychotic drug lurasidone inhibits coronaviruses by affecting multiple targets
2024 Baroni, Sara; Carletti, Tea; Donalisio, Manuela; Arduino, Irene; Cazzaniga, Irene; Giorgino, Toni; Esposito, Francesca; Porta, Alessia; Diomede, Luisa; De Luigi, Ada; Gobbi, Marco; Lembo, David; Marcello, Alessandro; Tramontano, Enzo; Milani, Mario; Mastrangelo, Eloise
A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint
2023 Guay Kevin, P.; Ibba, Roberta; Kiappes, J. L.; Vasiljević, Snezana; Bonì, Francesco; DE BENEDICTIS, Maria; Zeni, Ilaria; Le Cornu James, D.; Hensen, Mario; Chandran Anu, V.; Kantsadi Anastassia, L.; Caputo Alessandro, T.; Blanco Capurro Juan, I.; Bayo, Yusupha; Hill Johan, C.; Hudson, Kieran; Lia, Andrea; Brun, Juliane; Withers Stephen, G.; Martí, Marcelo; Biasini, Emiliano; Santino, Angelo; DE ROSA, Matteo; MILANI DE MAYO DE MARI, Mario; Modenutti Carlos, P.; Hebert Daniel, N.; Zitzmann, Nicole; Roversi, Pietro
A novel hotspot of gelsolin instability triggers an alternative mechanism of amyloid aggregation
2021 Bollati, Michela; Diomede, Luisa; Giorgino, Toni; Natale, Carmina; Fagnani, Elisa; Boniardi, Irene; Barbiroli, Alberto; Alemani, Rebecca; Beeg, Marten; Gobbi, Marco; Fakin, Ana; Mastrangelo, Eloise; MILANI DE MAYO DE MARI, Mario; Presciuttini, Gianluca; Gabellieri, Edi; Cioni, Patrizia; DE ROSA, Matteo
Combined in silico and in vitro approaches identified the antipsychotic drug lurasidone and the antiviral drug elbasvir as SARS-CoV2 and HCoV-OC43 inhibitors
2021 Milani, Mario.; Donalisio, M.; Bonotto, R. M.; Schneider, E.; Arduino, I.; Boni', Francesco.; Lembo, D.; Marcello, A.; Mastrangelo, E.
Structure-based identification of a new IAP-targeting compound that induces cancer cell death inducing NF-kappa B pathway
2021 Cossu, Federica; Camelliti, Simone; Lecis, Daniele; Sorrentino, Luca; Majorini, Maria Teresa; Milani, Mario; Mastrangelo, Eloise
Synthesis and Characterization of Novel Mono- And Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult
2021 Gornati, D; Ciccone, R; Vinciguerra, A; Ippati, S; Pannaccione, A; Petrozziello, T; Pizzi, E; Hassan, A; Colombo, E; Barbini, S; Milani, M; Caccavone, C; Randazzo, P; Muzio, L; Annunziato, L; Menegon, A; Secondo, A; Mastrangelo, E; Pignataro, G; Seneci, P
Computational and experimental characterization of NF023, a candidate anticancer compound inhibiting cIAP2/TRAF2 assembly
2020 Cossu, Federica; Sorrentino, Luca; Fagnani, Elisa; Zaffaroni, Mattia; MILANI DE MAYO DE MARI, Mario; Giorgino, Toni; Mastrangelo, Eloise
Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties
2020 Dal Cortivo, G; Marino, V; Boni, F; Milani, M; Dell'Orco, D
Modulation of guanylate cyclase activating protein 1 (Gcap1) dimeric assembly by ca2+ or mg2+: Hints to understand protein activity
2020 Boni, Francesco; Marino, Valerio; Bidoia, Carlo; Mastrangelo, Eloise; Barbiroli, Alberto; Dell'Orco, Daniele; Milani, Mario
Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
2020 Muzio, L; Sirtori, R; Gornati, D; Eleuteri, S; Fossaghi, A; Brancaccio, D; Manzoni, L; Ottoboni, L; Feo, Ld; Quattrini, A; Mastrangelo, E; Sorrentino, L; Scalone, E; Comi, G; Marinelli, L; Riva, N; Milani, M; Seneci, P; Martino, G
The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties
2020 DE ROSA, Matteo; Barbiroli, Alberto; Boni', Francesco; Scalone, Emanuele; Mattioni, Davide; Vanoni Maria, A.; Patrone, Marco; Bollati, Michela; Mastrangelo, Eloise; Giorgino, Toni; MILANI DE MAYO DE MARI, Mario
An alternative non-proteolytic mechanism may underlie AGel amyloidosis
2019 Bonì F; Milani M; Mastrangelo E; Babiroli A; Diomede L; de Rosa M
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions
2019 Cannalire R; Tarantino D; Piorkowski G; Carletti T; Massari S; Felicetti T; Barreca ML; Sabatini S; Tabarrini O; Marcello A; Milani M; Cecchetti V; Mastrangelo E; Manfroni G; Querat G
High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion
2019 Bollati, M; Scalone, E; Bonì, F; Mastrangelo, E; Giorgino, T; Milani, M; de Rosa, M
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Structural snapshots of the aldol condensation reaction of the enzyme trans-o-hydroxybenzylidenepyruvate hydratase-aldolase from Pseudomonas fluorescens N3 | 1-gen-2025 | Ferrara, Silvia; Braggiotti, Bianca; Mastrangelo, Eloise; Di Gennaro, Patrizia; Bertoni, Giovanni; Milani, Mario | |
| 4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses | 1-gen-2024 | Puxeddu, M.; Donalisio, M.; Bugert, J. J.; Corona, A.; Cocomazzi, P.; MILANI DE MAYO DE MARI, Mario; Hucke, F.; Arduino, I.; Esposito, F.; Moretti, P.; Ortore, M. G.; Nalli, M.; Manetto, S.; Mazzoccanti, G.; Bigogno, C.; Dondio, G.; Scio, P.; Coluccia, A.; Fracella, M.; Antonelli, G.; Lembo, D.; Tramontano, E.; Silvestri, R.; Mastrangelo, E.; La Regina, G. | |
| Acid-sensing ion channel 3 is a new potential therapeutic target for the control of glioblastoma cancer stem cells growth | 1-gen-2024 | Balboni, Andrea; D'Angelo, Camilla; Collura, Nicoletta; Brusco, Simone; Di Berardino, Claudia; Targa, Altea; Massoti, Beatrice; Mastrangelo, Eloise; Milani, Mario; Seneci, Pierfausto; Broccoli, Vania; Muzio, Luca; Galli, Rossella; Menegon, Andrea | |
| CHCHD4 binding affects the active site of apoptosis inducing factor (AIF): Structural determinants for allosteric regulation | 1-gen-2024 | Fagnani, E.; Cocomazzi, P.; Pellegrino, S.; Tedeschi, G.; Scalvini, F. G.; Cossu, F.; Da Vela, S.; Aliverti, A.; Mastrangelo, E.; Milani, M. | |
| Notte Europea delle Ricercatrici e dei Ricercatori 2024: Grande come un virus | 1-gen-2024 | Massa, Claudia; Mastrangelo, Eloise; Bollati, Michela; Cossu, Federica; Zoppè, Monica; Milani De Mayo De Mari, Mario; De Rosa, Matteo; Ferrara, Silvia; Boni', Francesco. | |
| Stabilization of the retromer complex: Analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface | 1-gen-2024 | Fagnani, E.; Bonì, F.; Seneci, P.; Gornati, D.; Muzio, L.; Mastrangelo, E.; MILANI DE MAYO DE MARI, Mario | |
| The antipsychotic drug lurasidone inhibits coronaviruses by affecting multiple targets | 1-gen-2024 | Baroni, Sara; Carletti, Tea; Donalisio, Manuela; Arduino, Irene; Cazzaniga, Irene; Giorgino, Toni; Esposito, Francesca; Porta, Alessia; Diomede, Luisa; De Luigi, Ada; Gobbi, Marco; Lembo, David; Marcello, Alessandro; Tramontano, Enzo; Milani, Mario; Mastrangelo, Eloise | |
| A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint | 1-gen-2023 | Guay Kevin, P.; Ibba, Roberta; Kiappes, J. L.; Vasiljević, Snezana; Bonì, Francesco; DE BENEDICTIS, Maria; Zeni, Ilaria; Le Cornu James, D.; Hensen, Mario; Chandran Anu, V.; Kantsadi Anastassia, L.; Caputo Alessandro, T.; Blanco Capurro Juan, I.; Bayo, Yusupha; Hill Johan, C.; Hudson, Kieran; Lia, Andrea; Brun, Juliane; Withers Stephen, G.; Martí, Marcelo; Biasini, Emiliano; Santino, Angelo; DE ROSA, Matteo; MILANI DE MAYO DE MARI, Mario; Modenutti Carlos, P.; Hebert Daniel, N.; Zitzmann, Nicole; Roversi, Pietro | |
| A novel hotspot of gelsolin instability triggers an alternative mechanism of amyloid aggregation | 1-gen-2021 | Bollati, Michela; Diomede, Luisa; Giorgino, Toni; Natale, Carmina; Fagnani, Elisa; Boniardi, Irene; Barbiroli, Alberto; Alemani, Rebecca; Beeg, Marten; Gobbi, Marco; Fakin, Ana; Mastrangelo, Eloise; MILANI DE MAYO DE MARI, Mario; Presciuttini, Gianluca; Gabellieri, Edi; Cioni, Patrizia; DE ROSA, Matteo | |
| Combined in silico and in vitro approaches identified the antipsychotic drug lurasidone and the antiviral drug elbasvir as SARS-CoV2 and HCoV-OC43 inhibitors | 1-gen-2021 | Milani, Mario.; Donalisio, M.; Bonotto, R. M.; Schneider, E.; Arduino, I.; Boni', Francesco.; Lembo, D.; Marcello, A.; Mastrangelo, E. | |
| Structure-based identification of a new IAP-targeting compound that induces cancer cell death inducing NF-kappa B pathway | 1-gen-2021 | Cossu, Federica; Camelliti, Simone; Lecis, Daniele; Sorrentino, Luca; Majorini, Maria Teresa; Milani, Mario; Mastrangelo, Eloise | |
| Synthesis and Characterization of Novel Mono- And Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult | 1-gen-2021 | Gornati, D; Ciccone, R; Vinciguerra, A; Ippati, S; Pannaccione, A; Petrozziello, T; Pizzi, E; Hassan, A; Colombo, E; Barbini, S; Milani, M; Caccavone, C; Randazzo, P; Muzio, L; Annunziato, L; Menegon, A; Secondo, A; Mastrangelo, E; Pignataro, G; Seneci, P | |
| Computational and experimental characterization of NF023, a candidate anticancer compound inhibiting cIAP2/TRAF2 assembly | 1-gen-2020 | Cossu, Federica; Sorrentino, Luca; Fagnani, Elisa; Zaffaroni, Mattia; MILANI DE MAYO DE MARI, Mario; Giorgino, Toni; Mastrangelo, Eloise | |
| Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties | 1-gen-2020 | Dal Cortivo, G; Marino, V; Boni, F; Milani, M; Dell'Orco, D | |
| Modulation of guanylate cyclase activating protein 1 (Gcap1) dimeric assembly by ca2+ or mg2+: Hints to understand protein activity | 1-gen-2020 | Boni, Francesco; Marino, Valerio; Bidoia, Carlo; Mastrangelo, Eloise; Barbiroli, Alberto; Dell'Orco, Daniele; Milani, Mario | |
| Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis | 1-gen-2020 | Muzio, L; Sirtori, R; Gornati, D; Eleuteri, S; Fossaghi, A; Brancaccio, D; Manzoni, L; Ottoboni, L; Feo, Ld; Quattrini, A; Mastrangelo, E; Sorrentino, L; Scalone, E; Comi, G; Marinelli, L; Riva, N; Milani, M; Seneci, P; Martino, G | |
| The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties | 1-gen-2020 | DE ROSA, Matteo; Barbiroli, Alberto; Boni', Francesco; Scalone, Emanuele; Mattioni, Davide; Vanoni Maria, A.; Patrone, Marco; Bollati, Michela; Mastrangelo, Eloise; Giorgino, Toni; MILANI DE MAYO DE MARI, Mario | |
| An alternative non-proteolytic mechanism may underlie AGel amyloidosis | 1-gen-2019 | Bonì F; Milani M; Mastrangelo E; Babiroli A; Diomede L; de Rosa M | |
| Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions | 1-gen-2019 | Cannalire R; Tarantino D; Piorkowski G; Carletti T; Massari S; Felicetti T; Barreca ML; Sabatini S; Tabarrini O; Marcello A; Milani M; Cecchetti V; Mastrangelo E; Manfroni G; Querat G | |
| High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion | 1-gen-2019 | Bollati, M; Scalone, E; Bonì, F; Mastrangelo, E; Giorgino, T; Milani, M; de Rosa, M |