Understanding the physiological role of CD30 would be an important forward in transplants because CD30+T cells can be indiced by alloantigens even in the presence of immunosoppressives and can act as regulatory cells in allograft. We hypothesize that the CD30 costimulator molecole is not a specific marker for TH2 cells in normal conditions, as has been suggested, but rather a marker for an important immunoregulatory subpopulation that regulates the balance between TH1 and TH2 type response.
CD30: an important costimulator molecule in the regulation of the balance between TH1/TH2 response
PELLEGRINI P;BERGHELLA AM;CONTASTA I;
2003
Abstract
Understanding the physiological role of CD30 would be an important forward in transplants because CD30+T cells can be indiced by alloantigens even in the presence of immunosoppressives and can act as regulatory cells in allograft. We hypothesize that the CD30 costimulator molecole is not a specific marker for TH2 cells in normal conditions, as has been suggested, but rather a marker for an important immunoregulatory subpopulation that regulates the balance between TH1 and TH2 type response.File in questo prodotto:
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