Enantiomeric pairs of 11 dansyl derivatives of -amino acids were used as analytes in electrokinetic chromatography to test the ability as chiral selectors of two pure derivatives of -cyclodextrin: the ethylendiamine derivative in primary position (CDen) and a member of a new class of receptors, the cysteamine-bridged hemispherodextrin THCMH. The selectivity obtained by the presence of the hemispherodextrin, appears particularly promising as shown by the large values of resolution obtained. The importance of a detailed analysis of these data is discussed in terms of suggestions for a rational approach to separation science.
High selectivity in new chiral separations of dansyl amino acids by cyclodextrin derivatives in electrokinetic chromatography
Giulia Grasso;
2007
Abstract
Enantiomeric pairs of 11 dansyl derivatives of -amino acids were used as analytes in electrokinetic chromatography to test the ability as chiral selectors of two pure derivatives of -cyclodextrin: the ethylendiamine derivative in primary position (CDen) and a member of a new class of receptors, the cysteamine-bridged hemispherodextrin THCMH. The selectivity obtained by the presence of the hemispherodextrin, appears particularly promising as shown by the large values of resolution obtained. The importance of a detailed analysis of these data is discussed in terms of suggestions for a rational approach to separation science.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
