Alkaline phosphatase and lactate dehydrogenase activities are inhibited by hematoporphyrin (HP) bound to live Yoshida hepatoma cells in the dark and, to a higher extent, upon illumination. The mechanistic implications of this observation are discussed and the proposal to investigate marker enzymes as sensitive probes of cell photodamage is presented.
Hematoporphyrin-sensitized photodamage of alkaline phosphatase and lactate dehydrogenase in Yoshida hepatoma cells
Baldacci S;
1985
Abstract
Alkaline phosphatase and lactate dehydrogenase activities are inhibited by hematoporphyrin (HP) bound to live Yoshida hepatoma cells in the dark and, to a higher extent, upon illumination. The mechanistic implications of this observation are discussed and the proposal to investigate marker enzymes as sensitive probes of cell photodamage is presented.File in questo prodotto:
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Descrizione: Hematoporphyrin-sensitized photodamage of alkaline phosphatase and lactate dehydrogenase in Yoshida hepatoma cells
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