Bulbs of Pancratium maritimum were found to contain a new glucosyloxy phenolic metabolise as well as 14 known Amaryllidaceae alkaloids. The structure of the phenolic metabolite was elucidated by spectroscopic and chemical methods, and it was identified as narciclasine-4-O-?-d-glucopyranoside. When tested in Artemia salina and potato disc assays the new glucoside showed cytotoxic and antitumour activity very similar to narciclasine
Narciclasine-4-O-b-D-glucopyranoside, a glucosyloxy amidic phenanthridone derivative from Pancratium maritimum
A De Giulio;
1991
Abstract
Bulbs of Pancratium maritimum were found to contain a new glucosyloxy phenolic metabolise as well as 14 known Amaryllidaceae alkaloids. The structure of the phenolic metabolite was elucidated by spectroscopic and chemical methods, and it was identified as narciclasine-4-O-?-d-glucopyranoside. When tested in Artemia salina and potato disc assays the new glucoside showed cytotoxic and antitumour activity very similar to narciclasineFile in questo prodotto:
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