Six novel minor polyacetylenic metabolites were isolated from the marine sponge Petrosia ficiformis by means of bioassay-directed purification. Spectral analysis led to partial structure determination, and the brine shrimp lethality assay on the pure compounds allowed a structur/activity relationship study. The potato disc antitumor assay and tests for the inhibition of fertilized sea urchin eggs were also conducted on the most abundant compounds
Minor bioactive polyacetylenes from Petrosia ficiformis
A De Giulio;
1990
Abstract
Six novel minor polyacetylenic metabolites were isolated from the marine sponge Petrosia ficiformis by means of bioassay-directed purification. Spectral analysis led to partial structure determination, and the brine shrimp lethality assay on the pure compounds allowed a structur/activity relationship study. The potato disc antitumor assay and tests for the inhibition of fertilized sea urchin eggs were also conducted on the most abundant compoundsFile in questo prodotto:
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