Candida cylindracea lipase suspended in anhydrous benzene was utilized to regioselectively acylate the Sa-hydroxyl group on several bile acid derivatives. Systematic investigations of the specificity of this lipase toward different steroid skeletons and a study of enzyme stability under the reaction conditions were also carried out.
Regioselective acylation of bile acid derivatives with Candida cylindracea lipase in anhydrous benzene
Riva S;Ottolina G;Secundo F;
1989
Abstract
Candida cylindracea lipase suspended in anhydrous benzene was utilized to regioselectively acylate the Sa-hydroxyl group on several bile acid derivatives. Systematic investigations of the specificity of this lipase toward different steroid skeletons and a study of enzyme stability under the reaction conditions were also carried out.File in questo prodotto:
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Descrizione: Regioselective Acylation of Bile Acid Derivatives with Candida cylindracea Lipase in Anhydrous Benzene
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