Objective. Stimuli activating vascular smooth muscle cell death can constrain the neointimal response to arterial damage and prevent vascular thickening. Conversely, endothelial cell death increases endothelial dysfunction and thrombosis risk. We investigated the combined effect of atorvastatin and TNF-alpha on vascular cell death.

Atorvastatin Sensitises Vascular Smooth Muscle Cells, but not Endothelial Cells, to TNF-alpha-induced Cell Death

2012

Abstract

Objective. Stimuli activating vascular smooth muscle cell death can constrain the neointimal response to arterial damage and prevent vascular thickening. Conversely, endothelial cell death increases endothelial dysfunction and thrombosis risk. We investigated the combined effect of atorvastatin and TNF-alpha on vascular cell death.
2012
Istituto di Endocrinologia e Oncologia Sperimentale ''G. Salvatore'' - IEOS
Vascular smooth muscle cells
endothelial cells
atorvastatin
TNF-alpha
cell death
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/130235
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? 4
social impact