Objective. Stimuli activating vascular smooth muscle cell death can constrain the neointimal response to arterial damage and prevent vascular thickening. Conversely, endothelial cell death increases endothelial dysfunction and thrombosis risk. We investigated the combined effect of atorvastatin and TNF-alpha on vascular cell death.

Atorvastatin Sensitises Vascular Smooth Muscle Cells, but not Endothelial Cells, to TNF-alpha-induced Cell Death

2012

Abstract

Objective. Stimuli activating vascular smooth muscle cell death can constrain the neointimal response to arterial damage and prevent vascular thickening. Conversely, endothelial cell death increases endothelial dysfunction and thrombosis risk. We investigated the combined effect of atorvastatin and TNF-alpha on vascular cell death.
2012
Istituto di Endocrinologia e Oncologia Sperimentale ''G. Salvatore'' - IEOS
18
38
6331
6338
8
Vascular smooth muscle cells
endothelial cells
atorvastatin
TNF-alpha
cell death
1
info:eu-repo/semantics/article
262
Giordano, Arturo; Romano, Simona; Nappo, Giovanna; Messina, Stefano; Polimeno, Michele; Corcione, Nicola; Cali, Gaetano; Ferraro, Paolo; Monaco, Mario...espandi
01 Contributo su Rivista::01.01 Articolo in rivista
none
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/130235
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