The crystal structure of the title compound, C20H14Cl3N3, a potent antifungal agent discovered recently, is here reported. The elucidation of the structure may be useful to provide a better understanding of the interaction of imidazole agents with P-450-dependent enzymes involved either in ergosterol biosynthesis (in fungi) or in hormones biosynthesis (in humans).
1-{[4-(4-chlorophenyl)-1H-pyrrol-3-yl](2,4-dichloro-phenyl)methyl}-1H-imidazole (RDS 416)
Camalli M;Pifferi A;
2001
Abstract
The crystal structure of the title compound, C20H14Cl3N3, a potent antifungal agent discovered recently, is here reported. The elucidation of the structure may be useful to provide a better understanding of the interaction of imidazole agents with P-450-dependent enzymes involved either in ergosterol biosynthesis (in fungi) or in hormones biosynthesis (in humans).File in questo prodotto:
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