The synthesis of potent inhibitors of matrix metalloproteinases (MMPs) bearing trifluoromethyl or difluoromethyl groups in purely aliphatic positions, and the effect of the incorporation of the fluoroalkyl functions on the inhibitory potency is presented.
Fluorinated inhibitors of matrix metalloproteinases
Viani F;Sani M;Zanda M
2007
Abstract
The synthesis of potent inhibitors of matrix metalloproteinases (MMPs) bearing trifluoromethyl or difluoromethyl groups in purely aliphatic positions, and the effect of the incorporation of the fluoroalkyl functions on the inhibitory potency is presented.File in questo prodotto:
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