The synthesis of potent inhibitors of matrix metalloproteinases (MMPs) bearing trifluoromethyl or difluoromethyl groups in purely aliphatic positions, and the effect of the incorporation of the fluoroalkyl functions on the inhibitory potency is presented.

Fluorinated inhibitors of matrix metalloproteinases

Viani F;Sani M;Zanda M
2007

Abstract

The synthesis of potent inhibitors of matrix metalloproteinases (MMPs) bearing trifluoromethyl or difluoromethyl groups in purely aliphatic positions, and the effect of the incorporation of the fluoroalkyl functions on the inhibitory potency is presented.
2007
Istituto di Chimica del Riconoscimento Molecolare - ICRM - Sede Milano
0-8412-7403-7
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/141985
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