N-acetyl-L-cysteine exerts a complex action on endometrial cells, involving regulation of gene expression and protein activity and location, all converging into a decreased proliferation and a switch toward a differentiating, less invasive, and less inflammatory phenotype. Also considering the lack of undesired side effects, including unaffected fertility potential, this suggests a beneficial use of NAC in endometriosis clinical treatment.

More than antioxidant: N-acetyl-L-cysteine in a murine model of endometriosis

2010

Abstract

N-acetyl-L-cysteine exerts a complex action on endometrial cells, involving regulation of gene expression and protein activity and location, all converging into a decreased proliferation and a switch toward a differentiating, less invasive, and less inflammatory phenotype. Also considering the lack of undesired side effects, including unaffected fertility potential, this suggests a beneficial use of NAC in endometriosis clinical treatment.
2010
FARMACOLOGIA TRASLAZIONALE - IFT
Inglese
94
7
2905
2908
Sì, ma tipo non specificato
8
info:eu-repo/semantics/article
262
Eugenia Pittaluga, A; Graziella Costa, A; K Krasnowska a, Ewa; Roberto Brunelli, B; Thomas Lundeberg, D; Maria Grazia Porpora, B; Daniela Santucci, C;...espandi
01 Contributo su Rivista::01.01 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/150089
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