This paper reports the study of terpene biosynthesis in the marine nudibranch Doriopsilla pelseneeri. In ViVo feeding experiments with 13C-glucose proved the de noVo origin of the terpene metabolites via a mevalonate pathway. Characterization of the stereochemical relationship of the new acetyl pelseneeriols (7 and 8) suggests a two-step mechanism for the sesquiterpene cyclization, leading to a slight refinement of terpene tailoring in this family of marine invertebrates.
Biosynthetic Evidence Supporting the Generation of Terpene Chemodiversity in Marine Mollusks of the genus Doriopsilla
Cutignano A;Cimino G;Fontana A
2008
Abstract
This paper reports the study of terpene biosynthesis in the marine nudibranch Doriopsilla pelseneeri. In ViVo feeding experiments with 13C-glucose proved the de noVo origin of the terpene metabolites via a mevalonate pathway. Characterization of the stereochemical relationship of the new acetyl pelseneeriols (7 and 8) suggests a two-step mechanism for the sesquiterpene cyclization, leading to a slight refinement of terpene tailoring in this family of marine invertebrates.File in questo prodotto:
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