Lipases from Candida antarctica and Mucor miehei catalyse efficiently the enantioselective esterification of rac-1-(3-trifluoromethylphenyl)propan-2-ol. This alcohol obtained in enantiopure form is suitable to prepare both the enantiomers of fenfluramine.
An Effective Enzymatic Resolution of rac-1-(3-Trifluoromethylphenyl)propan-2-ol Precursor of Fenfluramine
2002
Abstract
Lipases from Candida antarctica and Mucor miehei catalyse efficiently the enantioselective esterification of rac-1-(3-trifluoromethylphenyl)propan-2-ol. This alcohol obtained in enantiopure form is suitable to prepare both the enantiomers of fenfluramine.File in questo prodotto:
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