The physicochem. aspects of protein crystn. in reduced-gravity environments have been investigated with the Advanced Protein Crystn. Facility during six space missions. This review summarizes the results, dealing with the mechanisms of nucleation and crystal growth and with the quality of the crystals that were obtained under reduced gravity as well as under normal gravity on earth. Statistical analyses of the exptl. data strongly support the fact that microgravity has a pos. effect on crystn. and on crystal quality. A comparison of expts. and theories of protein crystn. in reduced-gravity environments is presented. Recommendations for improving the performance of protein crystn. expts. in mg and on earth are discussed.
Physical aspects of protein crystal growth investigated with the Advanced Protein Crystallization Facility in reduced-gravity environments.
2003
Abstract
The physicochem. aspects of protein crystn. in reduced-gravity environments have been investigated with the Advanced Protein Crystn. Facility during six space missions. This review summarizes the results, dealing with the mechanisms of nucleation and crystal growth and with the quality of the crystals that were obtained under reduced gravity as well as under normal gravity on earth. Statistical analyses of the exptl. data strongly support the fact that microgravity has a pos. effect on crystn. and on crystal quality. A comparison of expts. and theories of protein crystn. in reduced-gravity environments is presented. Recommendations for improving the performance of protein crystn. expts. in mg and on earth are discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
