Calix[4]arenes bearing thymine, adenine, cytosine, guanine 20-deoxynucleotide residues have been synthesized following the phosphoramidite chemistry. Hybrid compounds 2ad and 3ad represent the first example of nucleotides linked to the calixarene lower rim by a phosphoester bond. Preliminary studies about their assembling in apolar solvent and host properties toward biologically interesting guests are also reported.
Novel nucleotide-calixarene conjugates via phosphoester linkage
Granata G;Cunsolo F;Geraci C
2006
Abstract
Calix[4]arenes bearing thymine, adenine, cytosine, guanine 20-deoxynucleotide residues have been synthesized following the phosphoramidite chemistry. Hybrid compounds 2ad and 3ad represent the first example of nucleotides linked to the calixarene lower rim by a phosphoester bond. Preliminary studies about their assembling in apolar solvent and host properties toward biologically interesting guests are also reported.File in questo prodotto:
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