Nine linear polyoxygenated acetylenes, fulvynes A-I (1-9), exhibiting the uncommon 2-yne carboxylic acid functionality, have been isolated from the butanolic extract of the Mediterranean sponge Haliclona fulva. Their structures possess a long alkyl chain with several oxygenated carbons, and were established by detailed spectroscopic analysis. All fulvynes were found to be active against a chloramphenicol-resistant strain of Bacillus subtilis.
Fulvynes, antimicrobial polyoxygenated acetylenes from the Mediterranean sponge Haliclona fulva
Nuzzo Genoveffa;Ciavatta Maria Letizia;Villani Guido;Manzo Emiliano;
2012
Abstract
Nine linear polyoxygenated acetylenes, fulvynes A-I (1-9), exhibiting the uncommon 2-yne carboxylic acid functionality, have been isolated from the butanolic extract of the Mediterranean sponge Haliclona fulva. Their structures possess a long alkyl chain with several oxygenated carbons, and were established by detailed spectroscopic analysis. All fulvynes were found to be active against a chloramphenicol-resistant strain of Bacillus subtilis.File in questo prodotto:
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