La synthèse à haut rendement d'amides substitués ou non est décrite. La réaction est caractérisée par la modération de ses conditions expérimentales et sa facilité de mise en oeuvre. Une librairie d'amides a été générée par réaction entre les esters 1 ou 2 avec différentes amines.
Efficient synthesis of unsubstituted and substituted amides is described. The reaction is characterised by its mildness and ease of work-up. A library of amides, synthesised by heating ester 1 or 2 with various amines has been generated.
Neat reaction of carboxylic acid methyl ester and amines for efficient parallel synthesis of scaffold amide libraries
Machetti Fabrizio;
2003
Abstract
Efficient synthesis of unsubstituted and substituted amides is described. The reaction is characterised by its mildness and ease of work-up. A library of amides, synthesised by heating ester 1 or 2 with various amines has been generated.File in questo prodotto:
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