A detailed conformational characterization of a synthetic analogue of the peptide antibiotic alamethicin has been achieved by X-ray diffraction. The high-resolution structure of this analogue, which incorporates a spin probe, paves the way for a better understanding of the mode of action of alamethicin.

Crystal structure of a spin-labeled, channel-forming alamethicin analogue

Marco Crisma;Claudio Toniolo
2007

Abstract

A detailed conformational characterization of a synthetic analogue of the peptide antibiotic alamethicin has been achieved by X-ray diffraction. The high-resolution structure of this analogue, which incorporates a spin probe, paves the way for a better understanding of the mode of action of alamethicin.
2007
Istituto di Chimica Biomolecolare - ICB - Sede Pozzuoli
antibiotics
membranes
peptides
structure elucidation
X-ray diffraction
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/169755
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