Statistical analysis of the profiles of palindromic DNA molecules imaged by atomic force microscopy provided evidence of the capability of a mica surface of recognizing DNA sequences. The differential free energy involved in this collective recognition process was estimated. A tentative model based on sequence-dependent imbalances of the electrostatic field normal to the surface (E) along the chain is proposed.
Recognition on the nanoscale of a DNA sequence by an inorganic crystal surface
2006
Abstract
Statistical analysis of the profiles of palindromic DNA molecules imaged by atomic force microscopy provided evidence of the capability of a mica surface of recognizing DNA sequences. The differential free energy involved in this collective recognition process was estimated. A tentative model based on sequence-dependent imbalances of the electrostatic field normal to the surface (E) along the chain is proposed.File in questo prodotto:
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