Several cyclic oligodeoxynucleotides with different base composition and size have been prepared from 5?,3?-unprotected linear precursors, using a bifunctional phosphorylating reagent. The final deprotected ollgomers have been characterized by 1H- and 31P-NMR. The present procedure is particularly useful for millimolar scale syntheses.
One pot solution synthesis of cyclic oligodeoxyribonucleotides
Capobianco;
1990
Abstract
Several cyclic oligodeoxynucleotides with different base composition and size have been prepared from 5?,3?-unprotected linear precursors, using a bifunctional phosphorylating reagent. The final deprotected ollgomers have been characterized by 1H- and 31P-NMR. The present procedure is particularly useful for millimolar scale syntheses.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
