Intra-aortic balloon counterpulsation (IABC) is one of the methods to assist circulation. Its application is supposed to increase coronary blood flow (Qcor) and myocardial oxygen supply. Mechanical ventilation of the lungs causes some side effects that influence mainly hemodynamics: decreases cardiac output (CO) and systemic aortic pressure (Pas) but increases systemic venous pressure (Pvs). The aim of the study was to assess the influence of IABC on hemodynamic parameters in cases when mechanical ventilation of the lungs is used as well. We assumed pathological conditions of the heart as a reduced left ventricle elastance (Ea=0.77 mmHgocm-3) and increased left ventricle rest volume (Vo=10 cm3). Also peripheral systemic arterial resistance (Ras) took three different values. CARDIOSIM (C), a computer simulator of human cardiovascular system was used to assess the changes of hemodynamic parameters (CO, Qcor, Pas, Pap, and Pvs) when IABC and mechanical ventilation of the lungs were applied simultaneously. Computer simulation showed that application of IABC shifted into higher values such variables as Qcor (by ?22%), CO (by ?17%), maximum value of Pas (by ?20%), while left atrial pressure (Pla) was diminished (by ?30%). On the other hand Pvs and Pap were not strongly effected by IABC, but they were dramatically dependent on intrathoracic pressure, what means that Pvs, Pap and Pla should be carefully monitored during IABC and artificial ventilation
Hemodynamic parameters changes with intra-aortic balloon pumping and mechanical ventilation
De Lazzari C;Ferrari G;Clemente F
1998
Abstract
Intra-aortic balloon counterpulsation (IABC) is one of the methods to assist circulation. Its application is supposed to increase coronary blood flow (Qcor) and myocardial oxygen supply. Mechanical ventilation of the lungs causes some side effects that influence mainly hemodynamics: decreases cardiac output (CO) and systemic aortic pressure (Pas) but increases systemic venous pressure (Pvs). The aim of the study was to assess the influence of IABC on hemodynamic parameters in cases when mechanical ventilation of the lungs is used as well. We assumed pathological conditions of the heart as a reduced left ventricle elastance (Ea=0.77 mmHgocm-3) and increased left ventricle rest volume (Vo=10 cm3). Also peripheral systemic arterial resistance (Ras) took three different values. CARDIOSIM (C), a computer simulator of human cardiovascular system was used to assess the changes of hemodynamic parameters (CO, Qcor, Pas, Pap, and Pvs) when IABC and mechanical ventilation of the lungs were applied simultaneously. Computer simulation showed that application of IABC shifted into higher values such variables as Qcor (by ?22%), CO (by ?17%), maximum value of Pas (by ?20%), while left atrial pressure (Pla) was diminished (by ?30%). On the other hand Pvs and Pap were not strongly effected by IABC, but they were dramatically dependent on intrathoracic pressure, what means that Pvs, Pap and Pla should be carefully monitored during IABC and artificial ventilationI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
