Non racemic t-Boc protected aminoalkyl ketones have been obtained starting from ?-stannylated (E)-allylamines through a high yielding two step procedure consisting of a Stille coupling and a subsequent Wacker oxidation. These compounds are useful intermediates for obtaining 2,6-disubstituted piperidines.
A new approach to non racemic saturated and unsaturated 5-aminoalkyl methyl ketones
Reginato Gianna;Mordini Alessandro;
2000
Abstract
Non racemic t-Boc protected aminoalkyl ketones have been obtained starting from ?-stannylated (E)-allylamines through a high yielding two step procedure consisting of a Stille coupling and a subsequent Wacker oxidation. These compounds are useful intermediates for obtaining 2,6-disubstituted piperidines.File in questo prodotto:
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