The mixt. of LiN(CHMe2)2 and KOCMe3 (LIDAKOR reagent) promotes smooth ring opening of oxiranes to afford allyl alcs. with good to excellent yields. Internal epoxyalkanes and large-sized epoxycycloalkanes give preferentially or exclusively (E)-alkenols. The regio- and stereochem. of the ring-opening reaction are essentially the consequence of syn-periplanar elimination mechanisms.
Facile isomerization of oxiranes to allyl alcohols by mixed metal bases
Mordini Alessandro;
1990
Abstract
The mixt. of LiN(CHMe2)2 and KOCMe3 (LIDAKOR reagent) promotes smooth ring opening of oxiranes to afford allyl alcs. with good to excellent yields. Internal epoxyalkanes and large-sized epoxycycloalkanes give preferentially or exclusively (E)-alkenols. The regio- and stereochem. of the ring-opening reaction are essentially the consequence of syn-periplanar elimination mechanisms.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
