The replacement of diseased tissues with biological substitutes with suitable biomechanical properties is one of the most important goal in tissue engineering. Collagen represents a satisfactory choice for scaffolds. Unfortunately, the lack of elasticity represents a restriction to a wide use of collagen for several applications. In this work, we studied the effect of human elastin-like polypeptide (HELP) as hybrid collagen-elastin matrices. In particular, we studied the biomechanical properties of collagen/HELP scaffolds ...
Human elastin polypeptides improve the biomechanical properties of three-dimensional matrices through the regulation of elastogenesis
Sibillano Teresa;De Caro Liberato;Giannini Cinzia;Comparelli Roberto;
2015
Abstract
The replacement of diseased tissues with biological substitutes with suitable biomechanical properties is one of the most important goal in tissue engineering. Collagen represents a satisfactory choice for scaffolds. Unfortunately, the lack of elasticity represents a restriction to a wide use of collagen for several applications. In this work, we studied the effect of human elastin-like polypeptide (HELP) as hybrid collagen-elastin matrices. In particular, we studied the biomechanical properties of collagen/HELP scaffolds ...File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
prod_295123-doc_101548.pdf
accesso aperto
Descrizione: Human elastin polypeptides improve the biomechanical properties of three-dimensional matrices through the regulation of elastogenesis
Tipologia:
Versione Editoriale (PDF)
Dimensione
976.91 kB
Formato
Adobe PDF
|
976.91 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
