Synthetic peptides represent first choice biomelecules, with respect to proteins and mAb, for the monitoring of population variability and receptor functionality associated to a tumor pathology due to their favorable pharmacokinetic profile. It has been demonstrated that the surface molecule integrin alfa-V beta-3 could be an ideal target for the interaction with melanoma directed radiolabeled peptides.....
Synthesis, in vitro and in vivo evaluation of new 99mTc-labeled cyclic RGDfK peptide monocationic complexes
Calderan A;Biondi B;Bolzati C;Refosco F;Salvarese N;Ruzza P
2012
Abstract
Synthetic peptides represent first choice biomelecules, with respect to proteins and mAb, for the monitoring of population variability and receptor functionality associated to a tumor pathology due to their favorable pharmacokinetic profile. It has been demonstrated that the surface molecule integrin alfa-V beta-3 could be an ideal target for the interaction with melanoma directed radiolabeled peptides.....File in questo prodotto:
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