A variety of chiral 6-hepten-1-ynes have been found to undergo cyclization to titanabicyclopentenes by (h2-propene)Ti(Oi-Pr)2 with excellent yields and degrees of exo-stereoselectivity depending on the substrate steric requirements. In the framework of a plausible cyclization mechanism several conformational features which can regulate the stereoinduction have been suggested. © 2000 Published by Elsevier Science Ltd.

Diastereoselectivity in the synthesis of bicyclic titanacyclopentenes from chiral 6-hepten-1-ynes

Francesca Cicogna;
2000

Abstract

A variety of chiral 6-hepten-1-ynes have been found to undergo cyclization to titanabicyclopentenes by (h2-propene)Ti(Oi-Pr)2 with excellent yields and degrees of exo-stereoselectivity depending on the substrate steric requirements. In the framework of a plausible cyclization mechanism several conformational features which can regulate the stereoinduction have been suggested. © 2000 Published by Elsevier Science Ltd.
2000
cyclisation; titanium; titanium compounds; enynes; diastereoselection.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/226829
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