A variety of chiral 6-hepten-1-ynes have been found to undergo cyclization to titanabicyclopentenes by (h2-propene)Ti(Oi-Pr)2 with excellent yields and degrees of exo-stereoselectivity depending on the substrate steric requirements. In the framework of a plausible cyclization mechanism several conformational features which can regulate the stereoinduction have been suggested. © 2000 Published by Elsevier Science Ltd.
Diastereoselectivity in the synthesis of bicyclic titanacyclopentenes from chiral 6-hepten-1-ynes
Francesca Cicogna;
2000
Abstract
A variety of chiral 6-hepten-1-ynes have been found to undergo cyclization to titanabicyclopentenes by (h2-propene)Ti(Oi-Pr)2 with excellent yields and degrees of exo-stereoselectivity depending on the substrate steric requirements. In the framework of a plausible cyclization mechanism several conformational features which can regulate the stereoinduction have been suggested. © 2000 Published by Elsevier Science Ltd.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
