(S)-(+)-1-bromo-2-methylbutane was investigated using vibrational circular dichroism (VCD). Experimental absorption and VCD spectra of (+)-1-bromo-2- methylbutane in CDCl3 solution were recorded in the 2000-900 cm-1 region, and they were compared with the ab initio predictions of absorption and VCD spectra obtained with density functional theory using the B3LYP/6- 31G* basis set for (S)-1-bromo-2-methylbutane. This comparison indicates that (+)-1-bromo-2-methylbutane is of the (S)configuration and exists in several conformations. The results obtained for (S)-(+)-1-bromo-2- methylbutane are also compared to those for (S)-(+)-3-(2-methylbutyl) thiophene, which indicates that the predominant conformations are influenced by the substitution of bromine with thiophene ring.
Conformational analysis of (S)-(+)-1-bromo-2-methylbutane and the influence of bromine on
2002
Abstract
(S)-(+)-1-bromo-2-methylbutane was investigated using vibrational circular dichroism (VCD). Experimental absorption and VCD spectra of (+)-1-bromo-2- methylbutane in CDCl3 solution were recorded in the 2000-900 cm-1 region, and they were compared with the ab initio predictions of absorption and VCD spectra obtained with density functional theory using the B3LYP/6- 31G* basis set for (S)-1-bromo-2-methylbutane. This comparison indicates that (+)-1-bromo-2-methylbutane is of the (S)configuration and exists in several conformations. The results obtained for (S)-(+)-1-bromo-2- methylbutane are also compared to those for (S)-(+)-3-(2-methylbutyl) thiophene, which indicates that the predominant conformations are influenced by the substitution of bromine with thiophene ring.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
