The first fluorescent glycerophosphoinositol probe was synthesized in moderate good yield (37%). The total synthesis applied a convergent synthetic strategy involving two successive coupling reactions between the three key moieties: myo-inositol, glycerol, and NBD-aminohexanoic acid. © Georg Thieme Verlag.
Glycerophosphoinositols: Total Synthesis of the First Fluorescent Probe Derivative
Greco G;D'Antona N;Gambera G;Nicolosi G
2014
Abstract
The first fluorescent glycerophosphoinositol probe was synthesized in moderate good yield (37%). The total synthesis applied a convergent synthetic strategy involving two successive coupling reactions between the three key moieties: myo-inositol, glycerol, and NBD-aminohexanoic acid. © Georg Thieme Verlag.File in questo prodotto:
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