Ganglioside GM1 mimics including (R)-2-hydroxy-3-cyclohexylpropionic acid or (R)-2-hydroxy-3-phenylpropionic acid as replacements for NeuAc are stronger cholera toxin binders than the parent ligand 2, which includes (R)-2-hydroxy-propionic acid.
Ganglioside GM1 mimics: Lipophilic substituents improve affinity for cholera toxin
Arosio D;
2003
Abstract
Ganglioside GM1 mimics including (R)-2-hydroxy-3-cyclohexylpropionic acid or (R)-2-hydroxy-3-phenylpropionic acid as replacements for NeuAc are stronger cholera toxin binders than the parent ligand 2, which includes (R)-2-hydroxy-propionic acid.File in questo prodotto:
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Descrizione: Ganglioside GM1 mimics: Lipophilic substituents improve affinity for cholera toxin
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