Abstract: Liquid matrices are currently used in matrix assisted laser desorption ionization (MALDI) of non-polar macromolecules, such as polystyrene. We investigated the possibility of using non-liquid compounds as matrices. A series of polystyrene samples was analyzed by MALDI using a time-of-flight (TOF) analyzer. We found that a solid matrix, namely 2-(4-hydroxyphenylazo)-benzoic acid, yields quality mass spectra. The MALDI-TOF spectra were used to measure the parameters which characterize the molecular weight distributions of the polystyrene samples. The values obtained by MALDI-TOF were in good agreement with those obtained by other methods.
2-(4-HYDROXYPHENYLAZO)-BENZOIC ACID - A SOLID-MATRIX FOR MATRIX-ASSISTED LASER-DESORPTION IONIZATION OF POLYSTYRENE
PUGLISI C;SAMPERI F
1994
Abstract
Abstract: Liquid matrices are currently used in matrix assisted laser desorption ionization (MALDI) of non-polar macromolecules, such as polystyrene. We investigated the possibility of using non-liquid compounds as matrices. A series of polystyrene samples was analyzed by MALDI using a time-of-flight (TOF) analyzer. We found that a solid matrix, namely 2-(4-hydroxyphenylazo)-benzoic acid, yields quality mass spectra. The MALDI-TOF spectra were used to measure the parameters which characterize the molecular weight distributions of the polystyrene samples. The values obtained by MALDI-TOF were in good agreement with those obtained by other methods.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
