Chemical chaperones: Protecting osmolytes play a crucial role in preventing protein denaturation in harsh environmental conditions of living organisms. Experimental evidence is provided for a mechanism of protein-fold stabilization by these molecules that is in accord with the hypothesis of a backbone-based osmophobic effect.

Single-Molecule-Level Evidence for the Osmophobic Effect

Brucale M
2011

Abstract

Chemical chaperones: Protecting osmolytes play a crucial role in preventing protein denaturation in harsh environmental conditions of living organisms. Experimental evidence is provided for a mechanism of protein-fold stabilization by these molecules that is in accord with the hypothesis of a backbone-based osmophobic effect.
2011
Istituto per lo Studio dei Materiali Nanostrutturati - ISMN
osmolytes · protein folding · scanning probe spectroscopy · single-molecule studies · transition states
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/241995
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