Eleven new thio-avarol derivatives (3-13) were synthesized. Their antimicrobial, brine shrimp lethality, and free radical scavenging activities and acetylcholinesterase inhibition, together with 12 already reported semisynthetic thioavarol derivatives (14-25), were evaluated. Structure-activity relationships among these thio derivatives were determined.
Synthesis and Biological Activities of Thio-avarol Derivatives
Carmine Iodice;Giuseppina Tommonaro;Salvatore De Rosa
2008
Abstract
Eleven new thio-avarol derivatives (3-13) were synthesized. Their antimicrobial, brine shrimp lethality, and free radical scavenging activities and acetylcholinesterase inhibition, together with 12 already reported semisynthetic thioavarol derivatives (14-25), were evaluated. Structure-activity relationships among these thio derivatives were determined.File in questo prodotto:
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