We have examined the murine genes encoding transcription factors E2F1, -3, -5 and -6 in gametes and early embryos. All genes are expressed as maternal transcripts and all are efficiently transcribed after the blastocyst stage. Between those two stages, each E2F mRNA is transcribed with a distinctive and unique pattern. E2F proteins are also differentially expressed and compartmentalized in pre-implantation embryos.

E2F transcription factors are differentially expressed in murine gametes and early embryos

Palena A;Lavia P
2000

Abstract

We have examined the murine genes encoding transcription factors E2F1, -3, -5 and -6 in gametes and early embryos. All genes are expressed as maternal transcripts and all are efficiently transcribed after the blastocyst stage. Between those two stages, each E2F mRNA is transcribed with a distinctive and unique pattern. E2F proteins are also differentially expressed and compartmentalized in pre-implantation embryos.
2000
Istituto di Biologia e Patologia Molecolari - IBPM
Inglese
97
1-2
211
215
5
Sì, ma tipo non specificato
E2F1
E2F3
E2F5
E2F6
transcription
mouse embryo
pre-implantation embryo
indirect immunofluorescence
subcellular localization
gametes
spermatogenesis
fertilization
cell division
replication
7
info:eu-repo/semantics/article
262
Palena, A; Mangiacasale, R; Magnano, Ar; Barberi, L; Giordano, R; Spadafora, C; Lavia, P
01 Contributo su Rivista::01.01 Articolo in rivista
none
   The role of the E2F/DP genes in control of cell proliferation and oncogenesis
   FP4
   BMH4961529
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/247281
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