An unprecedented one-pot reaction that allows the synthesis of diprotected amino alcohols from unprotected vinyl aziridines is reported. The results demonstrate the possibility to use various acyl chlorides in order to obtain differently functionalised fragments. Mechanistic insights are given. (C) 2013 Elsevier Ltd. All rights reserved.
New one-pot procedure for the synthesis of diprotected amino alcohols from unprotected vinyl aziridines
Righi Giuliana;Bovicelli Paolo;
2013
Abstract
An unprecedented one-pot reaction that allows the synthesis of diprotected amino alcohols from unprotected vinyl aziridines is reported. The results demonstrate the possibility to use various acyl chlorides in order to obtain differently functionalised fragments. Mechanistic insights are given. (C) 2013 Elsevier Ltd. All rights reserved.File in questo prodotto:
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