The correct execution of morphogenetic patterns and the homeostatic control of tissue integrity require that cell proliferation be tightly balanced against cell differentiation and death. Among cell-intrinsic mechanisms deputed to restraining cell proliferation, negative feedback loops have a prominent role, given their ability to operate on sensing the generation and/or accumulation of intracellular signals.

A pervasive role for MIG6 in restraining cell proliferation

2014

Abstract

The correct execution of morphogenetic patterns and the homeostatic control of tissue integrity require that cell proliferation be tightly balanced against cell differentiation and death. Among cell-intrinsic mechanisms deputed to restraining cell proliferation, negative feedback loops have a prominent role, given their ability to operate on sensing the generation and/or accumulation of intracellular signals.
2014
Istituto di Biologia Cellulare e Neurobiologia - IBCN - Sede Monterotondo Scalo
Istituto di Biochimica e Biologia Cellulare - IBBC
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/261816
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