Precisely targeted genetic manipulation of the laboratory mouse has been one of the most significant achievements in the field of modeling human genetic diseases. The availability of an ever-increasing number of mutants, and the ability of generating ever-more complex manipulations beyond the "simple" gene knockout, offer unprecedented possibilities for genetic experiments addressing complex questions. Thus, the mouse is getting closer and closer to the most powerful genetic models such as Drosophila.
Mouse as a Model for Human Disease
Baldini;Antonio
2010
Abstract
Precisely targeted genetic manipulation of the laboratory mouse has been one of the most significant achievements in the field of modeling human genetic diseases. The availability of an ever-increasing number of mutants, and the ability of generating ever-more complex manipulations beyond the "simple" gene knockout, offer unprecedented possibilities for genetic experiments addressing complex questions. Thus, the mouse is getting closer and closer to the most powerful genetic models such as Drosophila.File in questo prodotto:
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