SPM has been widely used for the operator independent assessment of functional and molecular differences in human PET or MRI brain images. Despite the large diffusion of dedicated image systems and protocols, the use of SPM methodology to preclinical studies have been described in a limited number of studies, particularly for PET. Aim of this work was to optimize and adopt SPM analysis for the identification of patterns of altered metabolism due to acute stress in rat brain using PET with 18F-FDG.
Acute stress studies in rats by 18FDG PET and SPM
Gallivanone F;Di Grigoli G;Gilardi MC;Moresco RM;Castiglioni I
2012
Abstract
SPM has been widely used for the operator independent assessment of functional and molecular differences in human PET or MRI brain images. Despite the large diffusion of dedicated image systems and protocols, the use of SPM methodology to preclinical studies have been described in a limited number of studies, particularly for PET. Aim of this work was to optimize and adopt SPM analysis for the identification of patterns of altered metabolism due to acute stress in rat brain using PET with 18F-FDG.File in questo prodotto:
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