In the following studies, we examined the effects of the chemotherapeutic drug doxorubicin on NGAL expression in drug sensitive and drug resistant breast and prostate cancer cells to determine if the expression of NGAL was different in the two different types of cells. Furthermore, we determined that NGAL is often upregulated in multi-drug resistant acute T-lymphoblastic leukemia cells.

Increased NGAL (Lnc2) expression after chemotherapeutic drug treatment

Evangelisti C;Chiarini F;Martelli AM;
2013

Abstract

In the following studies, we examined the effects of the chemotherapeutic drug doxorubicin on NGAL expression in drug sensitive and drug resistant breast and prostate cancer cells to determine if the expression of NGAL was different in the two different types of cells. Furthermore, we determined that NGAL is often upregulated in multi-drug resistant acute T-lymphoblastic leukemia cells.
2013
Istituto di Genetica Molecolare "Luigi Luca Cavalli Sforza"
NGAL
Chemotherapeutic drug treatment
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/281299
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