Calcium ions (Ca2+) regulate numerous and diverse aspects of cochlear and vestibular physiology. This review focuses on the Ca2+ control of mechanotransduction and synaptic transmission in sensory hair cells, as well as on Ca2+ signalling in non-sensory cells of the developing cochlea.

Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications

Mammano Fabio
2012

Abstract

Calcium ions (Ca2+) regulate numerous and diverse aspects of cochlear and vestibular physiology. This review focuses on the Ca2+ control of mechanotransduction and synaptic transmission in sensory hair cells, as well as on Ca2+ signalling in non-sensory cells of the developing cochlea.
2012
Istituto di Neuroscienze - IN -
Hearing
Inner ear
Transducer adaptation
Ca2+ channels
Cadherin 23
Protocadherin 15
Plasma-membrane Ca2+-ATPase
Prestin
Intracellular stores
Calcium release
Mitochondria
Ribbon synapse
Adenosine-5 '-triphosphate
Inositol 1
4
5-trisphosphate
Connexin 26
Connexin 30
Deafness
Mouse models
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/281825
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