We analysed the concentrations of molecular lipids by UPLC-MS in blood samples of 679 well-characterised individuals in whom liver-fat content was measured using proton magnetic resonance spectroscopy (H-1-MRS) or liver biopsy. The participants were divided into biomarker-discovery (n = 287) and validation (n = 392) groups to build and validate the diagnostic models, respectively.

Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids

Iozzo Patricia;
2013

Abstract

We analysed the concentrations of molecular lipids by UPLC-MS in blood samples of 679 well-characterised individuals in whom liver-fat content was measured using proton magnetic resonance spectroscopy (H-1-MRS) or liver biopsy. The participants were divided into biomarker-discovery (n = 287) and validation (n = 392) groups to build and validate the diagnostic models, respectively.
2013
Istituto di Fisiologia Clinica - IFC
Inglese
56
10
2266
2274
9
Sì, ma tipo non specificato
Lipidomics
Mass spectrometry
Non-alcoholic fatty-liver disease
21
info:eu-repo/semantics/article
262
Oresic, Matej; Hyotylainen, Tuulia; Kotronen, Anna; Gopalacharyulu, Peddinti; Nygren, Heli; Arola, Johanna; Castillo, Sandra; Mattila, Ismo; Hakkarain...espandi
01 Contributo su Rivista::01.01 Articolo in rivista
none
   Hepatic and adipose tissue and functions in the metabolic syndrome
   HEPADIP
   FP6
   18734
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/285273
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