Parallel synthesis of a small library of hydroxy functionalized bicyclic lactams with optically pure mimicking dipeptide Pro-Ser has been accomplished via aldol condensation of aldehyde 9 with N-BocGlyCO(2)Et. The configurations of eight scaffolds were established unambiguously by NMR spectroscopy
Synthesis of conformationally restricted and optically pure analogues of serine-proline dipeptide via aldolic condensation
Manzoni L;
2004
Abstract
Parallel synthesis of a small library of hydroxy functionalized bicyclic lactams with optically pure mimicking dipeptide Pro-Ser has been accomplished via aldol condensation of aldehyde 9 with N-BocGlyCO(2)Et. The configurations of eight scaffolds were established unambiguously by NMR spectroscopyFile in questo prodotto:
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Descrizione: Synthesis of conformationally restricted and optically pure analogues of serine-proline dipeptide via aldol condensation
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