Objectives: To investigate the performance of different assays to detect anti-AQP4 antibodies.
Background: Antibodies against aquaporin-4 (AQP4), a water channel particularly expressed on perivascular astrocytic podocytes, are proposed as a marker for the diagnosis of neuromyelitis optica (NMO). However, a consensus on seroprevalence and optimal detection method has not yet been reached.
Antiacquaporin 4 antibodies detection by different techniques in neuromyelitis optica patients
Malosio M L;
2009
Abstract
Background: Antibodies against aquaporin-4 (AQP4), a water channel particularly expressed on perivascular astrocytic podocytes, are proposed as a marker for the diagnosis of neuromyelitis optica (NMO). However, a consensus on seroprevalence and optimal detection method has not yet been reached.File in questo prodotto:
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