The synthesis of a novel carbapenem antibiotic, 1beta-methyl PS-5, is described. The key step. involved the ester enolate-metalloimine cycloaddition.
BETA-LACTAMS FROM ESTER ENOLATES AND N-(TRIMETHYLSILYL)IMINES - A SIMPLE ROUTE TO 1-BETA-METHYL PS-5
BANDINI E;
1993
Abstract
The synthesis of a novel carbapenem antibiotic, 1beta-methyl PS-5, is described. The key step. involved the ester enolate-metalloimine cycloaddition.File in questo prodotto:
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