Scope of the review: The current review discusses the possible interplay between the viral mechanisms modulating cell homeostasis and redox sensitive mechanisms. Experimental data and indirect evidences are presented on the activity of viral dependent functions on i) the regulation of enzymes and compounds involved in OS; ii) the protection from oxidation of detoxifying/antiapoptotic enzymes and redox-sensitive transcription factors; iii) the suppression of apoptosis; and iv) the modulation of host microRNAs regulating genes associated with antioxidant defense.

Redox control of viral carcinogenesis: The human papillomavirus paradigm

Foppoli Cesira;
2015

Abstract

Scope of the review: The current review discusses the possible interplay between the viral mechanisms modulating cell homeostasis and redox sensitive mechanisms. Experimental data and indirect evidences are presented on the activity of viral dependent functions on i) the regulation of enzymes and compounds involved in OS; ii) the protection from oxidation of detoxifying/antiapoptotic enzymes and redox-sensitive transcription factors; iii) the suppression of apoptosis; and iv) the modulation of host microRNAs regulating genes associated with antioxidant defense.
2015
Istituto di Biologia e Patologia Molecolari - IBPM
Inglese
1850
8
1622
1632
11
Sì, ma tipo non specificato
Human papillomavirus
Oxidative stress
Cervical cancer
Antioxidant systems
Transcription factors
1
info:eu-repo/semantics/article
262
Foppoli, Cesira; De Marco, Federico; Cini, Chiara; Perluigi, M.
01 Contributo su Rivista::01.01 Articolo in rivista
none
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/304830
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