The European Mouse Mutant Archive (EMMA) is a non-profit repository for the collection, archiving (via cryopreservation) and distribution of relevant mutant strains essential for basic biomedical research. The EMMA network is currently formed by a partnership of 16 nodes in 13 different countries. EMMA is supported by the partner institutions, national research pro- grammes and by the EC's FP7 Capacities Specific Programme, through the INFRAFRONTIER- I3 EC grant (2013-2016), where the production of new transgenic lines, associated phenotyping activities, cryopreservation and archiving tasks are jointly addressed by a larger group of partners, 23 scientific partners from 15 European countries and Canada. EMMA's primary objective is to establish and manage a unified repository for maintaining biomedically relevant mouse mutants and making them available to the scientific community. Therefore, EMMA archives mutant strains and distributes them to request- ing researchers. At present, EMMA holds more than 5000 mouse strains, corresponding to transgenic mice, different type of mutants, gene-traps, knock-ins, knock-outs from the scientific community, and also including some targeted alleles from Deltagen, Lexicon and IKMC/IMPC projects. EMMA represents the third largest archive world-wide for mouse lines of interest in Biomedicine. EMMA's technology development programme is focusing on further improving sperm cryopreservation methods by implementing CARD-University of Kumamoto protocols, setting ICSI protocols, implementing and developing techniques to allow the shipment of refrigerated, unfrozen mouse embryos and epididymis, or frozen sperm in dry ice, without the need of using liquid nitrogen, and the use of non-surgical solutions for embryo transfer. EMMA also hosts cryopreservation courses, at MRC-Harwell and at CNR-Monterotondo, in collaboration with The Jackson Laboratory, to promote the use and dissemination of frozen embryos and spermatozoa. All EMMA procedures and all required information to deposit or request mouse lines from EMMA are easily available through the INFRAFRONTIER web site at: www.infrafrontier.eu.
EMMA: The European mouse mutant archive
Mammano Fabio;
2016
Abstract
The European Mouse Mutant Archive (EMMA) is a non-profit repository for the collection, archiving (via cryopreservation) and distribution of relevant mutant strains essential for basic biomedical research. The EMMA network is currently formed by a partnership of 16 nodes in 13 different countries. EMMA is supported by the partner institutions, national research pro- grammes and by the EC's FP7 Capacities Specific Programme, through the INFRAFRONTIER- I3 EC grant (2013-2016), where the production of new transgenic lines, associated phenotyping activities, cryopreservation and archiving tasks are jointly addressed by a larger group of partners, 23 scientific partners from 15 European countries and Canada. EMMA's primary objective is to establish and manage a unified repository for maintaining biomedically relevant mouse mutants and making them available to the scientific community. Therefore, EMMA archives mutant strains and distributes them to request- ing researchers. At present, EMMA holds more than 5000 mouse strains, corresponding to transgenic mice, different type of mutants, gene-traps, knock-ins, knock-outs from the scientific community, and also including some targeted alleles from Deltagen, Lexicon and IKMC/IMPC projects. EMMA represents the third largest archive world-wide for mouse lines of interest in Biomedicine. EMMA's technology development programme is focusing on further improving sperm cryopreservation methods by implementing CARD-University of Kumamoto protocols, setting ICSI protocols, implementing and developing techniques to allow the shipment of refrigerated, unfrozen mouse embryos and epididymis, or frozen sperm in dry ice, without the need of using liquid nitrogen, and the use of non-surgical solutions for embryo transfer. EMMA also hosts cryopreservation courses, at MRC-Harwell and at CNR-Monterotondo, in collaboration with The Jackson Laboratory, to promote the use and dissemination of frozen embryos and spermatozoa. All EMMA procedures and all required information to deposit or request mouse lines from EMMA are easily available through the INFRAFRONTIER web site at: www.infrafrontier.eu.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
