Objectives: To study the effect of 2-IHDA on cell proliferation and apoptosis in FRTL-5 cells.

Although thyroid gland function is mainly under the control of pituitary TSH, other factors, such as iodine, play a role in this process. The thyroid is capable of producing different iodolipids such as 6-iodo-deltalactone and 2-iodohexadecanal (2-IHDA). It was shown that these iodolipids mimic some of the inhibitory effects of excess iodide on several thyroid parameters.

Inhibitory effects of 2-iodohexadecanal on FRTL-5 thyroid cells proliferation

Fusco Alfredo;
2015

Abstract

Although thyroid gland function is mainly under the control of pituitary TSH, other factors, such as iodine, play a role in this process. The thyroid is capable of producing different iodolipids such as 6-iodo-deltalactone and 2-iodohexadecanal (2-IHDA). It was shown that these iodolipids mimic some of the inhibitory effects of excess iodide on several thyroid parameters.
2015
Istituto di Endocrinologia e Oncologia Sperimentale ''G. Salvatore'' - IEOS
Objectives: To study the effect of 2-IHDA on cell proliferation and apoptosis in FRTL-5 cells.
Thyroid
Iodolipids
lodohexadecanal
Iodine
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/309771
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