While innate and adaptive immunity are very efficient in defending our organism and maintaining its functionality in normal conditions, there are situations in which immunity is not fully effective. Immunological frailty can be the consequence of various circumstances, in particular ongoing diseases and aging. How the weakened immune system can deal with incurring nanoparticles is a major concern. This chapter will summarize the most frequent situations of immunological frailty, in order to identify the population groups at risk, and review the scantly information available to date. © 2014 Elsevier Inc. All rights reserved.

Nanoparticles and Immunological Frailty

Boraschi;Diana
2013

Abstract

While innate and adaptive immunity are very efficient in defending our organism and maintaining its functionality in normal conditions, there are situations in which immunity is not fully effective. Immunological frailty can be the consequence of various circumstances, in particular ongoing diseases and aging. How the weakened immune system can deal with incurring nanoparticles is a major concern. This chapter will summarize the most frequent situations of immunological frailty, in order to identify the population groups at risk, and review the scantly information available to date. © 2014 Elsevier Inc. All rights reserved.
2013
Istituto di Tecnologie Biomediche - ITB
Inglese
Nanoparticles and the Immune System: Safety and Effects
69
75
9780124080850
http://www.scopus.com/record/display.url?eid=2-s2.0-84904228420&origin=inward
Aging
Disease
Immunological frailty
Risk groups
1
02 Contributo in Volume::02.01 Contributo in volume (Capitolo o Saggio)
268
none
Boraschi; Diana
info:eu-repo/semantics/bookPart
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   HUMUNITY
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   A common European approach to the regulatory testing of nanomaterials
   NANOREG
   FP7
   310584

   A pan-European infrastructure for quality in nanomaterials safety testing
   QUALITYNANO
   FP7
   262163
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/313304
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