A new synthetic strategy to get the PNA-3? DNA linker with the monomethoxytrityl (Mmt) group as temporary protection of the backbone to be used for the synthesis of PNA/DNA chimeras was employed and a convenient strategy to obtain Mmt PNA monomers was developed. The synthetic strategies take advantage of the introduction of the acid-labile Mmt- protecting group in the first step.
New synthesis of PNA-3? DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras
Domenica Musumeci;Carlo Pedone;
2004
Abstract
A new synthetic strategy to get the PNA-3? DNA linker with the monomethoxytrityl (Mmt) group as temporary protection of the backbone to be used for the synthesis of PNA/DNA chimeras was employed and a convenient strategy to obtain Mmt PNA monomers was developed. The synthetic strategies take advantage of the introduction of the acid-labile Mmt- protecting group in the first step.File in questo prodotto:
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